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Proud of the U.S. wire Tsui ni (NeoStrata) Founded in 1988, has become the marketing more than 60 countries world famous acid research and development firms. Founders dermatologist Dr. Eugene J. VanScott and Chinese American, Dr. YU Rui Jin Chemical (Dr. Ruey J. Yu) has long engaged in skin physiology and aging research, found that acid to improve skin keratosis, dryness, acne with a variety of aging symptoms and other issues have a significant effect, and in 1974 the first medical journal in Canada, published in dermatology research, opening wider use of AHA skin care. Dr Scott and Dr. Yu has received a "acid" father of honorific. Later, Scott doctors in 1998 will be American Academy of Dermatology as the "master of Dermatology", while Dr. Yu Ruijin were awarded in 2003 will be the first international gold medal of Dermatology, the father of two acid in Dermatology the majesty of community is evident.

Following the first generation of glycolic acid has been well received in the market after, Scott and Dr. Yu Ruijin doctors gradually developed a second generation of acid: gluconic acid lactone (Gluconolactone), the third generation of acid: lactose acid (Lactobionic Acid), than the traditional first-generation acid glycolic more out of moisture, oxidation, mild stimulation of the features do not allow the application of acid and then a large step.

Proud of the U.S. wire Tsui ni (NeoStrata) will develop into the various acid formulations proud of wire Tsui ni (NeoStrata) with Exuviance launch two brands in the market: Ni proud of wire Tsui (NeoStrata) sold only in health care access, The Exuviance marketing at the general public access.